Medication Information Leaflet
The following leaflet addresses the use of higher doses of amoxicillin and co-amoxiclav/amoxicillin-clavulanate in children when treating their infections.
Both Amoxicillin and Co-amoxiclav/ Amoxicillin-Clavulanate contain amoxicillin as the active ingredient. Amoxicillin belongs to a group of antibiotics known as penicillin, and is used to treat a wide range of infections caused by bacteria, including infections of the chest (pneumonia), middle ear (otitis media), sinuses (sinusitis), tonsils (tonsillitis), urinary tract, and skin and soft tissue.
High-dose amoxicillin (such as 80 to 90mg/kg/day) is usually prescribed to overcome the antibiotic resistance that has developed to the common bacteria that may cause these infections such as the following:
If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.
Inform your healthcare professional if:
Some common side effects that you may experience include
The symptoms of a drug allergy include one or more of the following:
Very rarely, this medication may cause severe watery and/or bloody diarrhea, fever and painful stomach cramps. This can happen one to two days after you start taking an antibiotic, up to several weeks after you finish taking the antibiotic. This is due to overgrowth of the bacterium, C. difficile, in the colon.
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Take probiotics at least 2 hours apart from antibiotics as the antibiotics may reduce the effectiveness of probiotics.
Depending on whether you are taking the tablet or the suspension; the storage conditions may differ. Ask your healthcare professionals about the proper storage conditions of the antibiotic you are taking.
Pack the medication into a bag and bring it back to the pharmacy where you received the medication from.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on January 2024
This article was last reviewed on Thursday, May 20, 2021